András Spät, MD, PhD

Professor Emeritus

Member of the Hungarian Academy of Sciences

Member of Academia Europaea

Department of Physiology

Faculty of Medicine

Semmelweis University

Location: Budapest IX., Tűzoltó u. 37-47.

Mailing address: H-1428 Budapest, PO Box 2, Hungary

e-mail: Spat@eok.sote.hu , Spat@t-online.hu

Curriculum Vitae of Dr. András Spät

Born: Budapest, Hungary, 7 November 1940

University studies:

1958-1964: Budapest (presently Semmelweis) University Medical School, Budapest

Degrees:

1964: Doctor of Medicine

1975: Candidate of Sciences (corresponds to Ph.D.)

1982: Doctor of Sciences (in Medicine)

1993: Corresponding member of the Hungarian Academy of Sciences

1998: Full member of the Hungarian Academy of Sciences

1999: Member of the Academia Europaea

Jobs, positions:

in the Dept. of Physiology, Semmelweis University, Budapest:

1960-1962: research student

1962-1964: instructor

since 1964: staff member (assistant professor, lecturer, senior lecturer)

since 1986: Professor of Physiology

1995-2005: Head of Department

2010-: Professor Emeritus

Prizes and awards:

1967: Decoration for University Studies (donated by the Minister of Education)

1973: Géza Farkas Prize of the Hungarian Physiological Society

1980: research prize donated by the President of the Hungarian Academy of Sciences

1982: Decoration for Life Saving (donated by the Hungarian Government)

1987: “Academy Prize” of the Hungarian Academy of Sciences

1992: Albert Szent-Györgyi Prize (donated by the Minister of Education)

1992: European Medal of the Society for Endocrinology (U.K.)

1995: Arnold Ipolyi Award (National Science Foundation)

1996: Semmelweis Memorial Award (Semmelweis University, Budapest)

1997: Honoris Causa Pro Scientia Gold Medal (National Council of Scientific

          Research Students)

1998: Péter Pázmány Award for University Teaching (Pro Renovanda Cultura       Hungariae)

2002: Leo Szilárd Award (ALCOA Foundation and Hungarian Higher Education and Research Foundation)

2002: Batthyány-Strattman Prize (Minister of Health)

2004: Széchenyi Prize (President of the Republic)

2007: Fogarty Scholar

2023: Edit Gláz Memorial Award (Hungarian Society for Endocrinology and

 Metabolism)

Teaching activity in the Semmelweis University:

1962-1995: laboratory courses in Physiology

1967-2018: lectures on Physiology

1982-1995: supervisor of the laboratory courses in Physiology

1990-2000: Chairman of the Union of Research Students

1993-2007: head of the ‘Cellular and Molecular Physiology’ PhD Program           

PhD students and/or coworkers who have been awarded the PhD

Péter Enyedi

Tamás Balla

László Hunyady

György Hajnóczky

Gábor Rohács

Péter Várnai

Gábor Mikala

György Szabadkai

Ferenc Deák

Gábor Petheő

Judit Makara

Zoltán Molnár

János Pitter

Gergő Szanda

Professors who were members of Spät’s team

Balla Tamás (NIH, Bethesda MD)

Enyedi Péter

Fazekas Árpád

Hajnóczky György (Philadelphia, PA)

Hunyady László

Ludwig Endre

Rohàcs Tibor (New Jersey)

Sarkadi Balázs

Szabó Béla (Freiburg)

Szabadkai György (London)

Vàrnai Péter

Positions abroad:

1968-1969: Institute for Experimental Hormone Research, University of Copenhagen, Copenhagen, Denmark (Prof. Ejgil Bojesen, 6 months)

1984-1985: Dept. of Pharmacology, Medical College of Virginia, Richmond, VA (Prof. R.P. Rubin, 1 year)

1989-1990: Professeur Invité Louis Jeantet, Institute of Clinical Biochemistry,  University of Geneva, Geneva, Switzerland (Prof. C.B. Wollheim, 1 year)

Scientific publications:

4 university textbooks (coauthor)

2 monographies (in Hungarian)

5 monography chapters (in English)

132 publications in recognized scientific journals (in English)

https://vm.mtmt.hu/search/slist.php?lang=0&AuthorID=10000514

Cumulative impact factor: before 1975: » 26.5, between 1975 and 2018 : 453

Citations: > 5400

Hirsch index: 37

Former coworkers who were elected as member of the Hungarian Academy of Sciences

Balázs Sarkadi

László Hunyady

Tamás Balla (external member)

György Hajnóczky (external member)

Gergely Lukács (external member)

Scientific committees and editorial boards:

1969-1993: Editorial Board of the Journal of Steroid Biochemistry and Molecular Biology

1991-1996: chairman of the Section of Physiological Sciences of the National Science Foundation (OTKA, Hungary)

1991-2004: chairman of the Endocrinological Committee of the Council for Medical Research (ETT, Hungary)

1993-1997: Executive Committee of the Association of the European Journal of Endocrinology

1996-1998: Board of the University Research and Development Grants (Hungary)

1997-2010: chairman of the Habilitation Committee of the Semmelweis University

1997-2006: vice-president of the National PhD and Habilitation Committee (Hungary)

1997 – : Editorial Board of Magyar Tudomány

1998 – : Editorial Board of Acta Physiologica Acad. Sci. hung.

2004-2009 : Editorial Board of  Physiological Reviews

2005 – : Editorial Board of  Cell Calcium 

Specific scientific interest: molecular endocrinology, signal transduction

Scientific activity:

1962-1963: demonstration of the effect of aldosterone on intestinal sodium and potassium transport

1964-1969: studies on the role of the kidney in the control of aldosterone secretion in the rat

1970-1974: demonstration of the aldosterone secretory effect of prostaglandins

1971-1973: development of a protein binding assay for corticosterone, first application of aldosterone RIA in rat experiments

1974-1981: studies on the role of prostaglandins in the control of aldosterone secretion, analysis of the role of angiotensin II, potassium and ACTH in the induction of hyperaldosteronism in the sodium-depleted rat

1981-1985: demonstration of the role of calmodulin in glomerulosa cells, description of calcium compartments in glomerulosa cells, analysis of the effects of angiotensin II on phosphoinositide and calcium metabolism in glomerulosa cells, demonstration of the aldosterone stimulatory action of vasopressin

1985-1987: development of the technique of high specific activity labelling of inositol 1,4,5-trisphosphate (IP3), description and characterization of IP3 receptors in permeabilized cells and subcellular fractions from several tissues (hepatocytes, polymorphonuclears and liver, pituitary, adrenal cortex, resp.), description of the interaction of IP3 and IP4 in  pituitary microsomes

1987-1989: demonstration of Na+/H+ and Na+/Ca²⁺ antiporters in glomerulosa cells, studies on Ca2+ influx mechanisms in glomerulosa cells

1990-1992: analysis of the mechanism of depolarization and its role in the induction of Ca²⁺ influx in angiotensin-stimulated glomerulosa cells; demonstration of the activation of mitochondrial metabolism by cytoplasmic Ca²⁺ signal in intact

1990-1993: intracellular localization of IP3 receptor, characterization of various subtypes of IP3 receptor in glomerulosa cells

1992-1994: demonstration of Ca²⁺ – induced formation of NAD(P)H in intact cells

1993-1995: characterization of Ca²⁺ channel subtypes in glomerulosa cells

1993-2018: studies on mitochondrial Ca²⁺ uptake and on the effect of Ca²⁺  signal on mitochondrial  metabolism and Ca²⁺ -dependent cAMP formation in mitochondria

Publications https://m2.mtmt.hu/gui2/?type=authors&mode=browse&sel=10000514&view=pubTable

Last updated October 2023