Dr. Spät András

professor emeritus

Semmelweis Egyetem, ÁOK Élettani Intézet

CV

Curriculum Vitae of Dr. András Spät

 

 

Born: Budapest, Hungary, 7 November 1940

 

University studies:

1958-1964: Budapest (presently Semmelweis) University Medical School, Budapest

 

Degrees:

1964: Doctor of Medicine

1975: Candidate of Sciences (corresponds to Ph.D.)

1982: Doctor of Sciences (in Medicine)

1993: Corresponding member of the Hungarian Academy of Sciences

1998: Full member of the Hungarian Academy of Sciences

1999: Member of the Academia Europaea

 

Jobs, positions:

in the Dept. of Physiology, Semmelweis University, Budapest:

1960-1962: research student

1962-1964: instructor

since 1964: staff member (assistant professor, lecturer, senior lecturer)

1986-2010: Professor of Physiology

1995-2005: Head of Department

2010-:    Professor Emeritus

 

Teaching activity in the Semmelweis University:

1962-1995: laboratory courses in Physiology

1967-2017: lectures on Physiology

1982-1995: supervisor of the laboratory courses in Physiology

1990-2000: Chairman of the Union of Research Students

1993-2007: head of the ‘Cellular and Molecular Physiology’ PhD Program

 

Scientific publications (as on 30 May 2018)

4 university textbooks (coauthor)

2 monographies (in Hungarian)

5 monography chapters (in English)

115 publications in recognized scientific journals (in English)

Cumulative impact factor: before 1975: » 26.5, since 1975: 430

Citations: > 4480

Hirsch index: 34

 

Prizes and awards:

1967: Decoration for University Studies (donated by the Minister of Education)

1973: Géza Farkas Prize of the Hungarian Physiological Society

1980: research prize donated by the President of the Hungarian Academy of Sciences

1982: Decoration for Life Saving (donated by the Hungarian Government)

1987: “Academy Prize” of the Hungarian Academy of Sciences

1992: Albert Szent-Györgyi Prize (donated by the Minister of Education)

1992: European Medal of the Society for Endocrinology (U.K.)

1995: Arnold Ipolyi Award (National Science Foundation)

1996: Semmelweis Memorial Award (Semmelweis University, Budapest)

1997: Honoris Causa Pro Scientia Gold Medal (National Council of Scientific

Research Students)

1998: Péter Pázmány Award for University Teaching (Pro Renovanda Cultura    Hungariae)

2002: Leo Szilárd Award (ALCOA Foundation and Hungarian Higher Education and Research Foundation)

2002: Batthyány-Strattman Prize (Minister of Health)

2004: Széchenyi Prize (President of the Republic)

2007: Fogarty Scholar

 

Positions abroad:

1968-1969: Institute for Experimental Hormone Research, University of Copenhagen, Copenhagen, Denmark (Prof. Ejgil Bojesen, 6 months)

1984-1985: Dept. of Pharmacology, Medical College of Virginia, Richmond, VA (Prof. R.P. Rubin, 1 year)

1989-1990: Professeur Invité Louis Jeantet, Institute of Clinical Biochemistry,  University of Geneva, Geneva, Switzerland (Prof. C.B. Wollheim, 1 year)

 

 

Professors who were members of Spät’s team

Balla Tamás (NIH, Bethesda MD)

Enyedi Péter

Fazekas Árpád

Hajnóczky György (Philadelphia, PA)

Hunyady László

Ludwig Endre

Rohàcs Tibor (New Jersey)

Sarkadi Balázs

Szabó Béla (Freiburg)

Szabadkai György (London)

Vàrnai Péter

 

 

Members of the Hungarian Academy of Sciences who were members of Spät’s team

Balázs Sarkadi

László Hunyady

Tamás Balla

György Hajnóczky

 

 

Scientific committees and editorial boards:

1969-1993: Editorial Board of the Journal of Steroid Biochemistry and Molecular Biology

1991-1996: chairman of the Section of Physiological Sciences of the (Hungarian) National Science Foundation

1991-2004: chairman of the Endocrinological Committee of the (Hungarian) Council for Medical Research

1993-1997: Executive Committee of the Association of the European Journal of Endocrinology

1996-1998: Board of the University Research and Development Grants

1997-2010: chairman of the Habilitation Committee of the Semmelweis University

1997-2006: vice-president of the National PhD and Habilitation Committee

1997 –                        : Editorial Board of Magyar Tudomány

1998 –        : Editorial Board of Acta Physiologica Acad. Sci. hung.

2004-2009 : Editorial Board of  Physiological Reviews

2005 –         : Editorial Board of  Cell Calcium

 

 

Specific scientific interest: molecular endocrinology, signal transduction

 

Scientific activity:

1962-1963: demonstration of the effect of aldosterone on intestinal sodium and potassium transport

 

1964-1969: studies on the role of the kidney in the control of aldosterone secretion in the rat

 

1970-1974: demonstration of the aldosterone secretory effect of prostaglandins

 

1971-1973: development of a protein binding assay for corticosterone, first application of aldosterone RIA in rat experiments

 

1974-1981: studies on the role of prostaglandins in the control of aldosterone secretion, analysis of the role of angiotensin II, potassium and ACTH in the induction of hyperaldosteronism in the sodium-depleted rat

 

1981-1985: demonstration of the role of calmodulin in glomerulosa cells, description of calcium compartments in glomerulosa cells, analysis of the effects of angiotensin II on phosphoinositide and calcium metabolism in glomerulosa cells, demonstration of the aldosterone stimulatory action of vasopressin

 

1985-1987: development of the technique of high specific activity labelling of inositol 1,4,5-trisphosphate (IP3), description and characterization of IP3 receptors in permeabilized cells and subcellular fractions from several tissues (hepatocytes, polymorphonuclears and liver, pituitary, adrenal cortex, resp.), description of the interaction of IP3 and IP4 in  pituitary microsomes

 

1987-1989: demonstration of Na+/H+ and Na+/Ca2+ antiporters in glomerulosa cells, studies on Ca2+ influx mechanisms in glomerulosa cells

 

1990-1992: analysis of the mechanism of depolarization and its role in the induction of Ca2+ influx in angiotensin-stimulated glomerulosa cells; demonstration of the activation of mitochondrial metabolism by cytoplasmic Ca2+ signal in intact

 

1990-1993: intracellular localization of IP3 receptor, characterization of various subtypes of IP3 receptor in glomerulosa cells

 

1992-1994: demonstration of Ca2+ – induced formation of NAD(P)H in intact cells

 

1993-1995: characterization of Ca2+ channel subtypes in glomerulosa cells

 

1993-: studies on mitochondrial Ca2+ uptake and on the effect of Ca2+  signal on mitochondrial  metabolism

 

2013-2015: control of cAMP formation in mitochondria

 

2015- : effect of mitochondrial cAMP on mitochondrial calcium metabolism

 

 

Publications: https://vm.mtmt.hu/search/slist.php?lang=0&AuthorID=10000514

 

 

 


Semmelweis Kiválóság (Excellence)

Az adatok a Központi Könyvtár adatbázisából származnak. MTMT azonosító: 10000514

Tudományos társaság tisztségek, tagságok
Magyar Tudományos Akadémia Hazai 1993 Tag
Nemzetközi Akadémiai tagságok
Academia Europaea Akadémia 1999 Tag
Tudományos folyóirat szerkesztőségi, bírálói tagságok
Cell Calcium Nemzetközi 2005 Szerkesztő
European Journal of Endocrinology Nemzetközi 1993 - 1997 Egyéb
Journal of Steroid Biochemistry and Molecular Biology Nemzetközi 1969 - 1993 Szerkesztő
Magyar Tudomány Hazai 1997 Szerkesztő
Physiological Reviews Nemzetközi 2004 - 2009 Szerkesztő